Medial EarlySign

Intended Use

LGI-Flag™ is a computational software tool that is intended to identify individuals at risk for lower GI disorders that warrant further evaluation. It is based on complete blood count (CBC) patterns mainly related to erythrocyte features, measured and derived from peripheral venous blood specimens. LGI-Flag™ is indicated for use in individuals of the general population, between 50 and 75 years of age, who are not under active GI surveillance.

LGI-Flag™ 3.0 is recommended for use by healthcare systems and their affiliates (such as care providers and population health managers) within their Information Technology (IT) systems. LGI-Flag™ is an adjunct to established clinical guidelines and a referral for further evaluation should be based on the clinical judgment of the care provider.

Research findings: In conjunction with researchers at Roche and the National Taiwan University Hospital and College of Medicine in Taipei, the conclusions of the study demonstrated that LungFlag™ was able to work on Taiwanese EMR data and presented superiority over criteria based selection of individuals (USPSTF) and performed better than gold standard benchmark risk model PLCOm2012 that was adapted to be used on EMR data. The results were comparable to the previous validation studies and indicates that LungFlag™ can immediately support Taiwan screening program in identifying elevated risk populations among ever-smokers and potentially also on never-smokers populations.