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Solutions
Description
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Cyclica
Cyclica

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Human Longevity
Human Longevity

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Solutions

Description

Product Description:
Cyclica operates in the exciting intersection of Technology and Life Sciences/Healthcare. Cyclica enhances drug discovery by harnessing big data and predictive analytics through it's patented cloud based platform, Ligand Express™ (www.ligandexpress.com). Traditional design of small molecule therapies has focused on specific, disease-associated protein targets which has led to the development of many breakthrough medicines. However, once a drug enters the body it interacts with dozens, if not hundreds, of proteins before it is excreted. These off-target interactions can represent threats to the safety of a drug, or potential repurposing opportunities. Cyclica harnesses biophysics, biological data, and artificial intelligence (AI) to help pharmaceutical companies navigate the drug discovery pipeline by assessing the safety and efficacy of drugs. Whether pre-clinical, clinical, or FDA approved, Cyclica's patented, drug-centric, structure-based and AI-augmented platform, Ligand Express™ , offers novel insight and analysis into a drugs’ poylpharmacology (i.e. all the proteins a drug interacts with). By focusing on a small molecule structure and its polypharmacological profile, we distinguish ourselves with virtual screening technologies that are specific for a protein structure. We further augment our structural information with AI to drive our biophysical simulations. Learn more through a short video: https://www.youtube.com/watch?v=pYtLKSZB-r0 or by visiting our website at https://cyclicarx.com/ligandexpress/. Our publications, validation notes, and case studies can be found here: https://cyclicarx.com/documentation/
About Cyclica:
Cyclica operates in the exciting intersection of Technology and Life Sciences/Healthcare. Cyclica enhances drug discovery by harnessing big data and predictive analytics through it's patented cloud based platform, Ligand Express™ (www.ligandexpress.com). Traditional design of small molecule therapies has focused on specific, disease-associated protein targets which has led to the development of many breakthrough medicines. However, once a drug enters the body it interacts with dozens, if not hundreds, of proteins before it is excreted. These off-target interactions can represent threats to the safety of a drug, or potential repurposing opportunities. Cyclica harnesses biophysics, biological data, and artificial intelligence (AI) to help pharmaceutical companies navigate the drug discovery pipeline by assessing the safety and efficacy of drugs. Whether pre-clinical, clinical, or FDA approved, Cyclica's patented, drug-centric, structure-based and AI-augmented platform, Ligand Express™ , offers novel insight and analysis into a drugs’ poylpharmacology (i.e. all the proteins a drug interacts with). By focusing on a small molecule structure and its polypharmacological profile, we distinguish ourselves with virtual screening technologies that are specific for a protein structure. We further augment our structural information with AI to drive our biophysical simulations. Learn more through a short video: https://www.youtube.com/watch?v=pYtLKSZB-r0 or by visiting our website at https://cyclicarx.com/ligandexpress/. Our publications, validation notes, and case studies can be found here: https://cyclicarx.com/documentation/
Product Description:
Human Longevity, Inc. (HLI) is the genomic-based, health intelligence company empowering proactive healthcare and enabling a life better lived. HLI combines the largest database of genomic and phenotypic data with machine learning to drive discoveries and revolutionize the practice of medicine. HLI’s business areas include the HLI Health Nucleus, a genomic powered clinical research center which uses whole genome sequence analysis, advanced clinical imaging and innovative machine learning, along with curated personal health information, to deliver the most complete picture of individual health; HLIQ™ Whole Genome and HLIQ Oncology.
About Human Longevity:
Human Longevity, Inc. (HLI) is the genomic-based, health intelligence company empowering proactive healthcare and enabling a life better lived. HLI combines the largest database of genomic and phenotypic data with machine learning to drive discoveries and revolutionize the practice of medicine. HLI’s business areas include the HLI Health Nucleus, a genomic powered clinical research center which uses whole genome sequence analysis, advanced clinical imaging and innovative machine learning, along with curated personal health information, to deliver the most complete picture of individual health; HLIQ™ Whole Genome and HLIQ Oncology.

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Company Details

Founded in 2013

Founded in 2013

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