CRF Health develops electronic clinical outcome assessment (eCOA) solutions for home and site-based phase I-IV clinical trials for various therapeutic areas and patient populations in the United States and internationally. Its eCOA solutions include Patient Reported Outcomes, Observer Reported Outcomes, and Clinician or Rater Reported Outcomes. CRF Health also provides TrialMax Touch, a handheld diary that patients at home or the caregiver use, TrialMax Slate that is designed for use by clinicians and caregivers on the study site, TrialMax Web, a web-based diary that is primarily designed for late phase trials, TrialStudio that enables the client to design and adapt eCOA questionnaires, TrialManager, a role-based online portal that provides instant visibility to patient-reported data; medical device integration solutions, and TrialMax Synapse that links TrialMax to eClinical systems. Moreover, CFR Health offers project management, collaborative design, data management, real time trial management, data collection networks, and patient-facing helpdesk support services. It provides its solutions for central nervous system, gastrointestinal, genitourinary, infectious disease, pain, respiratory, and vaccine studies for pharmaceutical and biotechnology companies. Timo Ahopelto, Jarkko Joki-Tokola and Jaakko Ollila founded CRF in 2000, which became CRF Health, with its headquarters in Plymouth Meeting in Pennsylvania. It has locations in the United States, the United Kingdom, Finland, and Romania.