Dario Digital Therapeutics Solution and Platform

Dario delivers evidence-based, proven interventions and tools powered by intelligent software design, data science and human support—designed to create connections between member behaviors and health outcomes. For members, MyDario™ and the Dario program deliver real time data, tools and support to encourage proactive, positive changes to behavior that lead to health improvement and lower cost of care. The MyDario™ application provides immediate member feedback on behaviors impacting measurements, increasing the individual's correlation between cause and effect. The MyDario™ app provides a user focused decision support system that assists users to better understanding how their behaviors (food, substances, exercise, fatigue) and their mental health (stress, anxiety, loneliness) impact worsening or improvement in their chronic disease. All communications, whether AI or human driven, are closely tuned to member preferences and understanding, provide real-time personalized feedback.

Dario focuses on creating durable behavior change in chronic conditions including diabetes and hypertension. Individuals with these conditions are at higher risk of morbidity and mortality from COVID-19. By providing remote patient monitoring through engaging, easy to use devices and application, Dario helps those with chronic conditions safely social distance and stay healthy, while still maintaining connection to their health care providers.

Dario uses FDA approved devices and the application and devices are indicated for both adult and pediatric use.

Individuals with chronic conditions such as diabetes, obesity, metabolic syndrome, prediabetes and hypertension.

Dario recognizes that much of what creates worsening in chronic disease is behavior--the choices people make directly influence short and long-term outcomes. In order to truly improve outcomes in chronic disease, behavior change should not be the hardest thing to do--it should, in fact, be the easiest. Dario empowers members with clinically proven, easy to use tools and approaches that help them recognize, address and change the overlapping behaviors that cause worsening of their conditions. The program includes: Program Focus: Diabetes, hypertension, pre-diabetes, obesity and behavioral conditions impacting chronic disease such as stress, anxiety and loneliness. Dario Devices: Easy to use digital devices that interface directly and simply with the member’s existing smart phone (IOS and Android), and include blood glucose, blood pressure monitors and weight scale MyDario™ App: available to download from the App Store Clinical indications upon data capture (e.g., weight increase/decrease, glucose in-range, blood pressure high/low) Contextual logging of the specific event and all its related data (e.g., location, carbs, food pictures, medication and insulin intake, physical activity, mood, time, notes) Real-time AI driven digital feedback and intervention based on positive/negative trends, cause/effect alerts, and lapse in clinical data capture over time In-app alerts with calls to action and positive messaging Automatic log-book: Records all user activities and presents clear trend graphs over time Dario Journey Engine: Behavior is a predominant driver of chronic disease. DarioHealth's unique approach to changing behavior is powered by its AI-driven Journey Engine. Applying tens of billions of data points from over 65,000 Dario users in combination with an individual's own data and preferences, the platform makes effective behavior change the path of least resistance through a personalized user experience. DarioEngage: A flexible, open platform that enables real-time coaching and support and direct viewing of digital inputs from devices and member. Coaching can be delivered by a Dario coach or a Client/Third Party coach. Dario Engage provides immediate data on member measurements and inputs, allowing for a rich coaching experience and data driven decision making.

Compared to Competitive Offerings Dario: 1. HIGHER RETURN ON INVESTMENT Lower price: Dario is priced 33-50% lower than competitive offerings Pay only for engaged members: Dario charges ONLY for members who are actively engaged in the program and demonstrating regular use. No device fee stacking: Dario does not double or tripling of PEMPM when an employee requires additional devices. 2. FULLY INTEROPERABLE: Dario Offers Open Platform, API, Data Sharing and Flexible Coaching- Data Sharing: Dario’s open platform allows data sharing to client or third-party platform Coaching by client, third party or Dario: DarioEngage web-based platform allows coaching to be driven by client, third party or Dario Interoperability: Dario supports API integration with client or third-party platforms 3. BROAD ADOPTION AND EXPERIENCE, DARIO IS LOVED BY USERS 65,000 users currently pay for Dario out of their own pockets 80% of paying users are still engaged at 12 months 15,000+ users access their MyDario™ application daily Apple App Store: 11,000+ reviews and 4.9 STARS Users Recommend Dario, with a Net Promoter Score (NPS) of 77 4. CLINICALLY VALIDATED: Demonstrates Robust and Validated Clinical and Financial Outcomes 11 published studies demonstrating both efficacy and user durability Study analytics that include 3.4 million Dario user measurements Studies with data from 40,000+ Dario users Durable outcomes measured over two years 50% reduction in hypoglycemic events 60% reduction in hyperglycemic events eHbA1c reduction of 1.4% resulting in projected cost reductions of $2,396 PEMPY