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Best Digital Therapeutics (DTx) Products

Best Digital Therapeutics (DTx) Products

Also referred to as digital therapeutics, these apps often include education, adherence, tracking, surveys, and care team communications.

Health systems have the opportunity to extent the reach and impact of care by leveraging digital apps that can help patients get treatment 24X7 at a fraction of the cost of episodic care. Impacts include improved patient experience and outcomes as well as reduced total cost of care. Apps for maternal care are helpful for that key demographic while others are more geared to adult, and senior populations. One promising area is the use of augmented and virtual reality therapeutics for pain management in the child and youth populations.

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Digital Therapeutics (DTx): Products


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Clinicians can order, deliver, and monitor care from one unified platform within their current workflow. These include everything from connected devices to services including meal delivery and transportation, from patient education to surveys and PROs. Looking to alleviate the disparity in healthcare delivery while recognizing common technologies most people share, Xealth helps health systems make digital health a competitive asset.

Xealth enables healthcare teams to order digital content and services as easily as they do medications today. Patients can then access these digital health prescriptions from the provider's portal, so that they can actively manage their health.

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product capabilities
Multimodal delivery options
Connected FDA-approved devices
Real-time data collection
Integration and interoperability
Data Collection
Integration & Interoperability
Analytics
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Leading Health System
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Paloma Health is a virtual specialty clinic focused on thyroid disease, specifically hypothyroidism. Paloma Health is a "full-stack" virtual clinic helping patients manage hypothyroidism and Hashimoto's from home. The offering includes at-home blood test kits, virtual visits with specialists and nutritionists, dietary and lifestyle interventions, and vitamin supplements. This combination has proven to be life changing for our patients' happiness and productivity when they are struggling to find the right care and have a myriad of symptoms all at once: depression, fatigue, weight gain, brain fog,. The barriers and burdens of traditional hypothyroid care are significant: patients bounce from endocrinologists to nutritionist to primary care. They struggle to find specialists who understand their condition. Paloma Health is a game changer for many patients!

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Leading Health System
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Leading Health System
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Leading Health System
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Leading Health System
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Biofourmis brings the right care to every person, no matter where they are. The company’s AI-driven solutions provide people everywhere with connected access to hospital-level services, virtual provider networks for remote care, and life-changing clinical trials—all without leaving their homes. Trusted by leading health systems, life science companies and patients alike, Biofourmis’ connected platform improves patient outcomes, accelerates drug development, and closes critical gaps in care—ultimately making science smarter, healthcare simpler, and patients healthier.

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product capabilities
Multimodal delivery options
Personalized care plans
Connected FDA-approved devices
Integration and interoperability
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key clients
Leading Health System
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Leading Health System
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Leading Health System
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Leading Health System
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A personalized experience that helps members understand their blood sugar, develop healthy lifestyle habits and improve glycemic control.

Our data-driven approach provides members with personalized, actionable and timely support to drive lasting outcomes.

Effortless Data Collection

  • Cellular meter provides real-time feedback for glucose reading
  • Unlimited strips remove barriers for checking
  • Food and activity tracking to understand lifestyle habits

Personalized Health Signals

  • Health challenges drive small changes for big wins
  • Health Nudges(TM) deliver calls to action when members are most receptive

Human-centered Approach

  • 24/7 remote monitoring with emergency outreach
  • 1:1 live coaching from Livongo expert coaches
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Leading Health System
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Leading Health System
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Leading Health System
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Leading Health System
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Diabetes prevention, made achievable.

A fully CDC-recognized program that helps members focus on lifestyle behavior change to prevent diabetes. 

Weight management, made achievable.

An evidence-based program that helps members manage their weight by focusing on lifestyle behavior change.

Our data-driven approach for both offerings provides members with personalized, actionable and timely support to drive lasting outcomes. 

Effortless Data Collection

  • Cellular scale provides seamless weigh-ins
  • Food and activity tracking to understand lifestyle habits

Personalized Health Signals

  • Lessons provide evidence-based strategies for healthy living
  • Health challenges drive small changes for big wins

Human-centered Approach

  • 1:1 live coaching from Livongo expert coaches
  • Coach-led online meet-ups for support and accountability


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Leading Health System
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Leading Health System
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Leading Health System
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Stress is a normal part of life that affects all of us, so many elements of modern life can cause stress, when they add up, they can start to feel insurmountable. It’s also common to find that our energy is not focused on the things that truly matter to us. Our stress programs are developed to help you work towards solutions that work for you and that you can sustain overtime, to create a healthy balanced life, ultimately offering welcome space from stress.
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Leading Health System
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Leading Health System
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Leading Health System
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Leading Health System
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Glooko Enterprise enables healthcare teams to effectively manage their entire diabetes population during and in-between appointments. This solution supports shared decision-making, aligns with patient care goals, and optimizes your team’s clinical workflow.
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product capabilities
Multimodal delivery options
Personalized care plans
Real-time data collection
Connected FDA-approved devices
Integration and interoperability
Data Collection
Analytics
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key clients
Leading Health System
Health system
Leading Health System
Health system
Leading Health System
Health system
Leading Health System
Health system
+50 verified clients
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The Spect Ophthalmic Camera is a product consisting of an Apple iPhone, a mobile application (app), and an optical lens attachment and illumination source. The mobile app is accessible to users via the Apple App Store (Apple Inc.) for use on Spect issued iPhone devices. The Spect Ophthalmic Camera consists of a mechanical adaptor with a telescopic feature that houses a high-quality glass fundoscopic lens, and a white-light LED illumination source. The images are transferred and stored to a separate product, the Spect Ocular System, where a physician can retrieve and review the images.
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RelieVRx (formerly EaseVRx) is the first and only FDA-authorized at-home immersive virtual reality (VR) pain treatment indicated as adjunctive treatment for chronic lower back pain (CLBP).1,2

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Leading Health System
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People with musculoskeletal injuries see their therapy providers in the clinic, but what happens to their recovery between visits? Our digital recovery app supplements in-person physical therapy and guides injured workers to faster, fuller recoveries.

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Leading Health System
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Leading Health System
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Buyer's Guide


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A Buyer's Guide to

Digital Therapeutics

About digital therapeutics
Digital therapeutics, also called DTx, is a digital capability that exists within the broader category of digital medicine. DTx solutions are evidence-based, clinically validated and scalable software applications used to treat, manage, and/or prevent a variety of diseases and disorders in order to improve health outcomes and reduce costs. In addition, solutions are provider-prescribed, include privacy and security protections, and have received approval from the appropriate regulatory bodies.
How digital therapeutics differ from other digital health solutions
Unlike general wellness apps, which are available to anyone and do not require review or approval from regulatory bodies, digital therapeutics are specifically created to be prescribed or recommended by healthcare professionals, and are subject to the same regulatory requirements as traditional medical treatments. When selecting digital therapeutics, health systems should take care to look for clinical evidence. These solutions will often be labeled as clinically validated, with readily available research studies to support this designation.
Many digital therapeutic solutions address specific health conditions–in particular, major chronic diseases and behavioral health conditions. Compared to remote monitoring solutions, which require continuous attention from care teams, digital therapeutics are designed for greater user independence from care team oversight and direct intervention.


Digital therapeutics can play a significant role in the navigation to value in healthcare by demonstrating positive health outcomes and reducing costs. They can also help organizations improve patient outcomes and satisfaction, as well as support population health management.
Amberly Diets
—Amberly Diets
—Amberly Diets Director, Care Transformation & AVIA Precision Medicine Expert

How digital therapeutics are used to deliver care plan content

After receiving prescriptions from their providers, patients interact with digital therapeutics and receive content and interventions in a variety of ways, including:
  • Customizable assessments to establish baseline clinical data and behaviors
  • Evidence-based intervention pathways assigned by providers
  • Personalized patient engagement that may include education, task lists, goal-setting and progress monitoring
  • Virtual coaching to educate patients on how behaviors affect outcomes

Reimbursement opportunities for digital therapeutics

Currently, the most common reimbursement pathways for digital therapeutics are through contracts between manufacturers and payers for service-based billing codes, i.e. the amount of time providers spend reviewing data. Certain remote monitoring and remote therapeutic monitoring CPT codes may be applicable, along with cognitive behavioral therapy-related codes in some cases.

The case for digital therapeutics

Digital therapeutics offer a multi-pronged value proposition to support revenue and address key health system challenges. When used to their maximum benefit, DTx solutions may provide some of the following advantages:
Expanded clinical workforce capacity. AI-driven digital therapeutic solutions require limited care team intervention, but still provide effective personalized recommendations to meet individual patient needs. This capability is likely to prove especially important as patient populations continue to age and expand,
Improved patient engagement and satisfaction. Patients receive tailored recommendations for their unique health conditions through frequent interaction with engaging interfaces. These frequent touchpoints can serve to motivate behavior change and care plan adherence, influence better care outcomes, and may ultimately drive patient satisfaction.
Reduced costs. As healthcare continues its shift toward value-based care, digital therapeutics can help health systems navigate this change by facilitating better health outcomes and potentially reducing preventable utilization.
Support for revenue-driving specialty service lines. Digital therapeutics provide more patients with convenient, accessible, and engaging ways to receive care, while freeing up providers to focus on more complex cases.
Tools to advance health equity. Digital therapeutics can cross geographic, linguistic, and cultural barriers to deliver personalized interventions to patients in their own languages and familiar environments. DTx solutions are also not constrained solely to uninterrupted broadband access, and can deliver interventions and collect data with only intermittent access.

Use cases for digital therapeutics

Digital therapeutics support a wide range of use cases across different populations and clinical activities, such as behavioral health, chronic condition management, and other specialty use cases.
In behavioral health, DTx can be used to treat a number of conditions, such as anxiety, depression, PTSD and substance use disorder. Beyond therapy and medication, DTx solutions offer a scalable third option for consumers, who can access clinically proven care plan content on their mobile or desktop devices and rely on it as a viable pathway to care. Current behavioral health solutions offer cognitive behavioral therapy, gamified ADHD and depression interventions, cognitive emotional tasks for depression, and functions to support parents with pediatric sleep, ADHD, and anxiety. In the substance use disorder space, DTx solutions can support abstinence and promote retention in treatment programs.
Among chronic disease patients, whose conditions generally require frequent interventions over a lifetime, DTx can provide daily coaching to support crucial behavior change and care plan adherence, including medication and exercise reminders and tips to manage symptoms. Providers can also prescribe DTx solutions to monitor vital signs, analyze data, and more readily identify signs of deterioration.

What leading digital therapeutics companies/solutions offer:

  • Multimodal delivery options that allow patients to choose how to engage. Options include desktop, mobile apps, text messaging, and other connected devices.
  • Personalized care plans that deliver customizable treatment. Leading solutions offer libraries of evidence-based medical and psychosocial intervention pathways. Content is delivered in accessible, personable language to meet patients where they are.
  • Connected FDA-approved devices as needed to monitor specific conditions. Devices should support automatic and/or patient-triggered data upload.
  • Real-time data collection and response with AI-driven coaching. In addition, health systems must work with solution companies to determine where this data flows and the associated care pathways.
  • Integration and interoperability with EHR and other relevant software. Leading solutions are accessible to providers in their native workflow and easily exchange data with other solutions, such as prescribing software.
Organizing for success with digital therapeutics


  • Start with the problem or vision to determine where a digital therapeutic may support the clinical workflow
    Before deploying a digital therapeutic, health system leaders should develop a vision or articulate a problem that a solution could address in order to improve patient care. Start by identifying the types of conditions that can be treated with a digital therapeutic. Systems should also establish key performance indicators to optimize the deployment process.
  • Seek provider buy-in
    As with virtually any new digital health solution, effective usage and scale depends on end user buy-in. It is important to ensure that DTx solutions are user friendly and can be seamlessly integrated into the clinical workflow. As such, engaging providers early on in the selection process, adoption can be accelerated.
  • Provide effective training
    DTx solutions must fit with existing provider workflows and health systems should provide ample training to ensure that providers understand the benefits of DTx solutions and how to use them effectively in patient care. Due to the evolving nature of digital therapeutics, this training should be ongoing to keep users up-to-date on solution capabilities.
  • Determine a strategy: build, buy, or partner
    Health systems may also want to assess whether it makes sense to adopt third-party solutions, configure existing tools, or build a software solution from scratch. Some organizations may find opportunities for private sector partnerships that allow them to develop solutions that can scale beyond a single health system and diversify revenue streams beyond clinical revenue.
  • Engage in a thoughtful tech selection process
    Third party validation, including reviews from other health systems, are crucial to help organizations identify the solutions with the greatest potential for success. In addition, health systems should explore solutions from their existing EHR vendors–many EHR companies offer native tools that can easily fit with existing workflows and architecture.
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