Best Pharmacogenomic (PGx) Decision Support Products

Pharmacogenomics, also called precision prescribing or referred to with the shorthand PGx, is the ability to use a network of knowledge to treat an individual patient by analyzing genetic information in combination with social, environmental and lifestyle factors. Digital pharmacogenomic solutions provide clinicians-most commonly in primary care, cardiology, behavioral health or oncology service lines-with targeted genomic testing and automated clinical decision support that analyzes all relevant data to deliver optimized drug and dosage recommendations. With medication regimens tailored to their drug metabolism and other health variables, patients are more likely to receive safe and effective medications the first time while avoiding drug failure or adverse reactions.Pharmacogenomics is a core component of precision medicine-the development of targeted therapies for individuals or sub-groups of patients based on their genetics, lifestyle, and environment.

When pharmacogenomic testing and precision prescribing is incorporated into direct patient care, a patient’s care journey may look like this:

1. The patient seeks care from a primary care physician, specialist, emergency department or urgent care.
2. The provider screens patients for relevant health conditions and assesses risk for adverse events (such as cardiovascular events or suicide risk).
3. The patient undergoes routine labs and a pharmacogenetic saliva or blood test.
4. A decision support platform analyzes test results and other relevant data to help the physician identify an appropriate care plan.
5. The patient receives a highly personalized care plan for their health condition.

• Screening: Blood or saliva tests that predict patient response to specific drugs, or comprehensive panels that assess several genes and provide data for many medications.
• Clinical decision support: EHR-integrated software solutions that assist physicians with screening recommendations and analyze screening results and patient health data to support precision dosing.

• Population health assessment: Solutions that analyze population-level data to identify medication-related risks and refine treatment recommendations for individuals.
• Medication therapy management: Solutions that help pharmacists and other providers more effectively tailor medication regimens to prevent adverse events.