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Solutions
Description
Compatibility Level
Clients
Use cases
EHR integrations
Client types
Awards
Differentiators
Keywords
Media
Company details
Jump to:
Categories
Solutions
Description
Compatibility Level
Clients
Use cases
EHR integrations
Client types
Awards
Differentiators
Keywords
Media
Company details
 GenoAct
GenoAct

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eCART
eCART

Categories

Solutions

Description

Product Description:
ActX is a genomic decision support service that is tightly integrated within the EHR. With ActX implemented, every time a prescription order is written in the routine medication order workflow, it will be checked for drug-genome interactions and the prescriber alerted as needed. Provider friendly, and CAP accredited initial results will be generated and returned to the provider in the clinical inbasket. A dynamic and up-to-date Genomic Profile for each patient will be available in their chart. Patient genetic data can be imported from any clinically valid source. The knowledgebase content is easily customizable and includes content for pharmacogenomics, actionable genetic risks, and carrier statuses.
About ActX, Inc.:

ActX helps physicians make better decisions about medical treatment, using patients’ genetic information. ActX uses its GenoACT℠ clinical decision support program to analyze a patient’s genetic information and alert physicians in real time through their existing workflow tool, the electronic health record, about drug-genome interactions, actionable hereditary risks and carrier status

Product Description:
  • eCART is a research-based, AI-driven software as a medical device (SaMD) that utilizes a machine learning algorithm to continuously assess hospitalized patients’ risk of impending death or intensive care unit (ICU) transfer, assisting medical staff in swift and accurate recognition of patients requiring increased medical attention. eCART draws upon readily available patient data from the EHR, rapidly quantifies disease severity, and predicts likelihood of critical illness onset, hours before it happens.
  • eCART received FDA 510(k) clearance in 2024, with clinical performance data of nearly two million hospitalizations from 21 hospitals, including an unprecedented level of real-world prospective data, to ensure consistent accuracy across geography, age, race, and top medical conditions (e.g. sepsis, COPD, heart failure). 
  • Built upon more than a decade of ongoing scientific research, eCART was developed at UChicago Medicine by Dr. Dana Edelson, MD, MS and Dr. Matthew Churpek, MD, PhD and is well chronicled in published literature. The analytic and workflow have been in use in clinical practice since 2016.
About AgileMD:

At AgileMD, we are building the most advanced real-time predictive analytics and clinical pathways platform for hospitals.

To date, AgileMD tools have been used on more than 4 million patient encounters by more than 135,000 clinical users in over 250 hospitals, including some of the nation's leading academic medical centers. AgileMD's eCART clinical deterioration prediction software is FDA cleared and the first AI-powered early warning device for ward patients to go through the FDA process with real-world prospective data. 

AgileMD is backed by premier start-up partners MATTER, YCombinator, and Rock Health, and our cutting-edge analytics are built on more than decade of ongoing research at the University of Chicago. In 2021, AgileMD garnered nearly $3 million in combined federal research and development funding from the U.S. Department of Health and Human Services (HHS), including the National Institutes of Health (NIH) and the Biomedical Advanced Research and Development Authority (BARDA).

Compatibility level

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Clients

Select which hospital or health system you work at and see the client list

Use Cases

Description:
  • Yale Generations project
  • NorthShore University Health System DNA 10k Program


Pediatric use cases:

Pharmacogenomics and actionable genetic risks.

Users:
  • Pharmacy
  • Lab
  • IT
  • All clinicians (including most specialties)
  • Genetics
  • Genetic Counselors
Description:

eCART anticipates all cause clinical deterioration in medical-surgical (ward) patients and is validated for sepsis, COPD, heart failure, and COVID-19. The EHR-embedded software device is used to prevent failure to rescue and improve timely ICU transfers using a highly-accurate risk score, an interpretable patient dashboard, and actionable clinical workflows.

Pediatric use cases:

pCART, the pediatric version of eCART, is available for research use and is used in clinical practice today. We would be happy to discuss a partnership.

Users:

Medical-surgical nurses and providers, rapid response & critical care teams

EHR Integrations

Integrations:

Acute care EMR, Ambulatory EMR, Patient portal, Pop health platform, Behavioral health, Community based organizations

EMR Integration & Relevant Hardware:

Required

EMRs Supported:

Epic, Cerner, Allscripts, eClinicalWorks, Athenahealth

Hardware Compatibility:

Not applicable

Integrations:

Acute care EMR

EMR Integration & Relevant Hardware:

Required

EMRs Supported:

Epic, Cerner

Hardware Compatibility:

Desktop

Client Types

Awards

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Differentiators

Differentiators vs EHR Functionality:

Please reach out to ActX for more information.

Differentiators vs Competitors:

Please reach out to ActX for more information.

Differentiators vs EHR Functionality:
  • Continuously monitors EHR data in real time
  • Stratifies hospitalized patients by risk of impending all-cause clinical deterioration and sepsis
  • Notifies inpatient providers when patient may need additional assessment and management
  • Recommends clinical pathways with integrated order entry
Differentiators vs Competitors:
  • Authorized: FDA 510(k) cleared
  • Tested: Derived and validated in nearly 3 million patient encounters across 28 hospitals
  • Experienced: 8+ years in clinical use; 10+ years of published academic literature on value over other early warning scores
  • Accurate: High sensitiviy and specificity, meaning fewer false alarms and more efficient focus on the highest risk patients
  • Integrated: Embedded cross-team workflow ensures that risk scores are not ignored and action is taken
  • Benchmarked: Robust reporting, benchmarking, and implementation support drive quality improvement

Keywords

Images

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Videos

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Downloads

ActX
https://www.agilemd.com/updates/ecart-fda-clearance

Alternatives

Company Details

Founded in 2012

Founded in 2011

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