Regulora is a PDT that is accessed through a smartphone app. It consists of seven therapy sessions provided over three months, with practice sessions between. Regulora is delivers Gut-Directed Hypnotherapy (GDH) and includes the collection of adherence data and patient reported outcomes using clinically-validated survey instruments. Unlike most digital therapeutics that focus on behavioral health issues, Regulora treats abdominal pain, a somatic symptom that is the chief IBS complaint. For decades, in-person psychological interventions have been effective in treating IBS but were accessible to very few patients.

Regulora provides broad access to this treatment through a mechanism familiar to both patients and doctors: obtaining a prescription. By providing physicians an easy way to prescribe treatment and patients a convenient way to undergo therapy privately at home, Regulora offers a non-drug option that addresses the stigma often associated with bowel problems and psychological interventions.

metaMe Health is a pioneer in developing Prescription Digital Therapeutics (PDTs). In 2022, our work was recognized by being included on the “50 on Fire” list of up-and-coming Chicago companies, being named one of the Top 150 most promising Digital Health Companies of 2022 nationwide by CBInsights, and being selected as a finalist in the LyfeBulb-Bristol Myers Squibb Inflammatory Bowel Disease Challenge. In 2021, our lead product Regulora® became the first FDA-cleared PDT specifically for abdominal pain associated with irritable bowel syndrome (IBS) in adults. More than 30 million Americans are affected by IBS, and the abdominal pain, diarrhea, and/or constipation that comes with it. Regulora provides relief by digitizing a standardized Brain-Gut therapy approach that has been clinically proven to be effective in reducing IBS symptoms.

Codex Health develops clinical intelligence solutions for healthcare providers to bring the power of data-driven decision making into healthcare workflows.

Non-drug therapy with no side effects

Codex Health proactively identifies at-risk patients, preventing them from having adverse events and avoiding unnecesary ED visits or readmission to the hospital.

We provide AI enabled technology and certified educators to to help patients understand and manage their complex condition. Codex is proven to improve clinical outcomes in a financially sustainable way.