Integrated, Not Isolated Data Collection The biggest challenge with RPM data is usually where it lives. With Locus, data doesn't sit in a separate portal: Direct to EHR: We feed "discrete data" directly into your EMR flowsheets from our ecosystem of both Bluetooth and Cellular connected devices which include common vital signs, as well as spirometry, fetal doppler, and growing. Manage by Exception: Our system filters the "noise." Instead of scrolling through thousands of normal readings, your team is alerted only when a patient’s data trends outside of their personal "normal" range. This is further fine-tuned by health system partners. Outcomes: Our data consistently demonstrates how remote monitoring has lowered readmission rates and/or shortened hospital stays.

Locus offers several methods for health systems to access and analyze their data: Reporting Dashboard: A built-in dashboard within the Locus web application that provides immediate visibility into program metrics. Custom SQL Reports: The platform supports the creation of specialized

Locus Health’s bidirectional communication capabilities are managed via feature flags, allowing health systems to customize the level of patient engagement based on specific program needs or clinical capacity. Feature Flag Customization Administrators can choose to enable or disable the following communication channels: In-App Messaging: This optional feature allows for secure, non-urgent messaging between the care team and the patient. Video Visits: Programs have the option to "Turn On" video capabilities for 1-to-1 visits or group sessions with up to 49 participants, such as centering sessions or group counseling. Notifications: Clinicians can enable or disable real-time notifications via email or SMS for measurement alerts and new messages. If these are disabled, alerts will still display within the web portal for the care team to manage. Patient notifications happen via HIPAA-compliant banner notifications and "nudges" to take vital signs or login to see a message.

Accessibility and WCAG Compliance Locus is committed to an "accessibility-first" design philosophy, adhering to international standards to ensure an inclusive digital experience: WCAG Compliant Design: The application is built following Web Content Accessibility Guidelines (WCAG), which focus on making digital content perceivable, operable, understandable, and robust for individuals with various disabilities. Native Accessibility Tool Support: The app is designed to work seamlessly with iOS and Android native mobile tools. This allows patients to utilize standard features such as: Screen Readers (e.g., VoiceOver on iOS and TalkBack on Android) for patients with visual impairments. Text Resizing and high-contrast modes to improve readability. Voice Control and other assistive technologies provided by mobile operating systems. Equitability and Localization To ensure health equity, Locus addresses linguistic and social barriers through targeted features: Language Localization: The Locus patient app is fully localized in English and Spanish, allowing a broader demographic to engage with their care plans in their preferred language. Flexible Access Options: Recognizing that not all patients have the same resources, Locus offers four ways to access the platform: BYOD (Bring Your Own Device): Use the app on a personal iPhone or Android device. Cellular-Enabled iPads: Locus can provide pre-configured, cellular-ready tablets for patients who do not have reliable internet or their own mobile devices. Web-Based Portal (PWA): A web-accessible version for use on any browser. Simple Connectivity: Features like cellular hub connectivity and automated data transmission help patients in rural or underserved areas stay connected without needing complex technical setups.

Pediatric Care Pathways Locus is a leader in pediatric remote patient monitoring (RPM), serving many of the top children's hospitals in the United States. Their pediatric pathways focus on "feeders and growers" and medically complex patients to reduce length of stay (LOS) and improve outcomes. Cardiac: High-risk cardiology, heart failure, VAD, TRAC, and exercise programs for older CHD patients. NICU: Complex discharges (NG tubes/Oxygen), feeders and growers, and substance-exposed newborns. Pulmonary: Asthma, Cystic Fibrosis, and Trach/Vent care. General/Other: Solid organ transplant, palliative care, outpatient antimicrobial therapy (OPAT), and the transition from TPN to oral feeds. Adult Care Pathways For adult populations, Locus provides pathways aimed at managing chronic conditions and reducing 30-day readmission risks. Oncology: Specifically developed through NIH/National Cancer Institute awards, including chemotherapy treatment and medication monitoring. Cardiac: Heart failure and cardiac rehab. Pulmonary: COPD and pneumonia. Surgical: Bariatric and urology pathways. General/Chronic: Endocrinology, high-risk obstetrics, mental health, weight management, and spinal cord injury. Transplant: Solid organ and stem cell transplant. Pathway Customization and Scalability While these pathways are prebuilt based on clinical evidence and established best practices, they remain highly flexible: Configurability: Care teams can choose from over 70 different measurement types to design a dashboard that fits their specific program needs. Enterprise Integration: Pathways are integrated directly into the EMR (e.g., Epic, Cerner), allowing for discrete data return and SSO access for clinicians. Logistics Support: Locus manages the full logistics of these pathways, including shipping branded kits with integrated devices (scales, BP monitors, etc.) directly to patients' homes.

The Locus platform is designed to be fully integrated into enterprise health systems. Key features include: Discrete Data Integration: Biometric and symptomatic data from remote monitoring is sent back to the EMR as discrete data, making it actionable within the patient's record. Single Sign-On (SSO): Clinicians can access the Locus dashboard directly through the EMR using SSO via SMART on FHiR, reducing the need for multiple logins. EMR-Based Enrollment: Programs can be configured to allow patient enrollment directly via an EHR order, as seen in implementations like the Inova health system. Patient Portal Integration: Patients can have the option to launch the Locus application directly from within their MyChart (Epic) portal. Appointment Synchronization: Locus can integrate with health system scheduling to provide appointment reminders and updates within the remote monitoring app. This includes incorporating schedules from an EMR, infusion, and transplant systems into one centralized reminder.

Locus Health provides a structured support model designed to ensure clinical continuity while maintaining efficient operational assistance for both providers and patients: 24/7/365 Urgent Support: Locus offers around-the-clock support every day of the year specifically for urgent care-blocking issues. This ensures that critical clinical workflows and monitoring remain functional at all times. Core Office Hours: Standard support services are available Monday through Friday, from 8:30 a.m. EST to 8:30 p.m. EST, excluding federal holidays. Logistics and Shipping Support: During office hours, the Locus team manages the logistics of picking, packing, and shipping branded kits directly to clinics or patient homes. Help Desk and Technical Assistance: The Locus Help Desk is available during office hours to assist with account activation and device connectivity support. Clinical and Patient Engagement: Support staff work during office hours to encourage patient engagement and provide necessary training for clinicians to ensure they are proficient with the platform.

Locus Health provides a highly configurable framework for health systems to deliver patient education and health coaching materials directly within the Locus app. To ensure a personalized and flexible patient journey, systems can utilize the following content delivery methods: Automated Delivery Logic: Content can be scheduled for auto-delivery based on specific milestones, such as how long a patient has been enrolled in a program. Manual Triggering for Individual Needs: Clinicians have the ability to manually trigger specific content to patients at any time. This ensures that educational resources and coaching tools are tailored to meet unique, patient-centered care requirements as they arise. Hosted Educational Content: Health systems can host a variety of multimedia resources, including PDFs and Videos, to provide clinical guidance and self-care instructions. Surveys and PROMs: Clinicians can integrate questionnaires and Patient Reported Outcome Measures (PROMs) to gather qualitative data and assess patient progress.

While Locus is primarily an enterprise remote patient monitoring solution, its flexible communication infrastructure enables specialized partnerships—such as with the Ollie Hinkle Heart Foundation—and supports remote cardiac rehab programs for both 12-week and 24-week sessions. These programs leverage Locus's bidirectional communication tools to achieve the following: 1-to-1 and Group Support Sessions: The platform can "turn on" video visit capabilities to host private consultations or group centering sessions for up to 49 participants. Structured Coaching Delivery: Health systems can host and auto-deliver educational PDFs, videos, and surveys tailored to the specific timeline of a 12 or 24-week cardiac recovery journey. Patient-Centered Adjustments: Clinicians can manually trigger specific coaching content or questionnaires based on a patient's individual progress or behavioral health requirements during rehab.

Locus has demonstrated its impact in oncology through the following partnerships and clinical studies: COVID-19 Oncology Management: Locus support enables managing oncology patients at home during treatment, a practice highlighted for its efficiency and safety during the COVID-19 pandemic. Inova Schar Cancer Institute Pilot: An NCI-funded pilot to remotely monitor gastrointestinal cancer patients with connected devices, symptomatic questions, combined infusion and EMR scheduling integration, complimented by HCO authored "What to Expect" video series. Wearable Oncology Trial: Locus participated in a prospective clinical trial titled "A Pilot Prospective Clinical Trial Using Remote Monitoring for Cancer Patients Undergoing Outpatient Chemotherapy" led by Dr. John Deeken. Study Focus: The trial utilized Apple Watch data (steps, sleep, activity) and symptomatic questions for patients starting cycle one, day one of chemotherapy and infusion. Awards: The Inova Schar Cancer Center received an Innovation Award in July 2021 from the Association of Cancer Care Centers for its work with Locus. NCI Grants and Research As an NIH/National Cancer Institute (NCI) SBIR Awardee (2021-2024) with a Phase 1 and Phase 2 award, Locus developed a compliment of advanced care oncology navigation features to work alongside their connected device, bidirectional communication, and EMR integration features

ThinkAndor® supports multilingual and omni-channel virtual visit sessions between patients and providers without the need for downloading an app. Via Andor’s digital front door, we provide patients with a model for navigating to the appropriate line of care through a first in the industry use of OpenAI/GPT capabilities. Patients can either schedule a synchronous virtual visit session or choose from a variety of asynchronous options. Patients can also add family members or caregivers in the virtual wait room and providers can invite colleagues for multi-disciplinary calls using the embedded ThinkAndor®AI Bot within the session. This whole process helps to improve how both patients and providers are brought together.

ThinkAndor® supports a comprehensive virtual waiting room with a fully configurable set of patient intake and assessment forms. In this process, providers can push patients to complete a device and browser check, review their symptoms, complete inclusion/exclusion criteria and upload images. Shortly before the visit, patients can add family members or care givers and improve accessibility through features like closed captioning. Providers/care team members can track a patient’s progress in the queue and alert them when the provider is ready to begin the session.

ThinkAndor® provides highly-resilient video call capabilities with the ability to toggle to phone/audio and support multi-party sessions. The presence of the ThinkAndor®AI Bot during visits acts to track time, surface clinically relevant content for the clinician, and create SOAP notes. Additionally, ThinkAndor® can support asynchronous communications for lower acuity conditions. These can be escalated to synchronous calls if a clinician determines that the patient’s status has degraded.

ThinkAndor®’s bidirectional integration with the client EHR allows users to leverage existing patient demographic/medical information and upload new documentation. Generative AI curates the content and context for the clinician from the virtual experience for clinical documentation prep and decision making. The ThinkAndor®AI Bot also facilitates an ambient experience in the virtual visit and captures the voice of the clinician to generate clinical documentation for the EHR, including SOAP notes. The dashboard allows clinicians to both monitor active signals from patient inputs and devices as well as review past documentation in the patient details. This improves workflow orchestration and enables faster interventions to yield improved patient outcomes.

ThinkAndor® has the ability to support eligibility, payment processing – including payment plans & copays, prescriptions, labs, orders, and referrals through third-party integrations and core host systems such as the client’s EHR. Relevant information from orders can be surfaced by the ThinkAndor®AI Bot and brought to the attention of providers through preconfigured alerts and escalation pathways. Because the ThinkAndor®AI Bot starts the session, it also captures the timing of the experience and the documentation to support billing for that particular visit. Post-visit, ThinkAndor® continues the experience by reaching out to the patient to ensure compliance with their care plan and any follow ups that may be required.

Andor Health provides both remote and on-site technical support as needed by customer institutions. Andor Health maintains a help desk to receive service-related inquiries from the client via designated means during the client’s business hours, excluding Andor Health observed holidays, and Andor provides clients with extended support outside of business hours via telephone for critical issues. Per the specific implementation and the client’s needs, Andor can stand up educational materials and assign the appropriate routing for patient concerns.

Through ThinkAndor®’s native capabilities and deep integrations with staffing partners, Andor can help fill chronic staffing shortages and address emergencies like burst capacity scenarios. For virtual nursing, virtual sitting, remote consults, and other bespoke virtual hospital use cases, including telestroke, telepsych, and virtual hospitalists, Andor can either leverage resources from other facilities within a health system or bring in credentialed resources from third parties. This both fills certain specialties which users may not already have staffed and allows for health systems to reduce costs by better matching resources to current capacity.

Andor Health uses PowerBI to provide robust analytics such as provider utilization/productivity, average time per visit, most commonly treated conditions, resolution vs. escalations, volume by day and time, and patient feedback. Andor Helath is also pioneering the use of OpenAI and GPT to provide insights and analytics along a patient’s care plan so that as data comes through, ThinkAndor™ can provide predictive analysis on the outcome of the patient.